Pacific professor to study tobacco addiction with $375K grant
Pacific University School of Pharmacy associate professor John Harrelson has received a three-year grant of $375,127 from the National Institute on Drug Abuse within the National Institutes of Health to investigate
new treatments for tobacco addiction.
Hell research the effectiveness of a dietary agent, cinnamaldehyde, which could help curb addiction. Cinnamaldehyde is a natural product that provides the characteristic aroma to cinnamon oil and cinnamon powder.
The teams preliminary research supported by grants from Oregon Health and Science Universitys Medical Research Foundation, Pacific Research Institute for Science and Mathematics, and Pacific University indicates that cinnamaldehyde is an inhibitor of a key enzyme that metabolizes nicotine.
The findings are significant
because previous studies show-
ed that differences in nicotine metabolism influence smoking behavior.