Shoni Schimmel's 27 points led Louisville to a 75-56 victory at home against Central Florida on Wednesday night.
The fifth-ranked Cardinals improved to 17-1 overall and 5-0 in the American Athletic Conference. UCF fell to 8-8, 1-3.
Schimmel, a senior guard from Franklin High, made 8 of 22 shots from the field, including 5 of 14 from 3-point range. She also had five rebounds, five assists and three turnovers.
Louisville led 42-26 at halftime.